Reversal by Imidazole Derivatives
نویسنده
چکیده
cus aureus by heat shock. The effect has then been more thoroughly investigated by landolo and Ordal (5, 6). Since heat shock causes an increased sensitivity of fungal cells to high temperature and blue light (2-4), it seemed justified also to test the response of heat-shocked fungal cells to high concentrations of sodium chloride. Most experiments were performed with the ascomycete Ophiostoma multiannulatum by using the method of quick preheating described
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Design and Synthesis of New Imidazole Derivatives of Captopril
A new series of alkylthio imidazole analogues of captopril, an ACE inhibitor used in the treatment of hypertension, was designed and synthesized in order to obtain agents more active than captopril with less side effects. All the compounds thus prepared were purified and characterized by IR, NMR and Mass analytical instruments.
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A new series of alkylthio imidazole analogues of captopril, an ACE inhibitor used in the treatment of hypertension, was designed and synthesized in order to obtain agents more active than captopril with less side effects. All the compounds thus prepared were purified and characterized by IR, NMR and Mass analytical instruments.
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